Jack Clark: - AI will make a Nobel Prize-winning discovery within 12 months (working collaboratively with humans) - Bipedal robots will help with enterprise work ("tradespeople") in 2 years - AI systems will be able to design their own successors by year-end 2028 (i.e., RSI) - Companies run solely by AI will be generating millions of USD in revenue within 18 months - Clark's most conservative prediction is that vast swathes of the economy and society will go through profound changes, potentially including "a machine economy decoupling from the human economy, robots gaining brains, science progressing without humans, and scientific equipment that people hadn't conveived of but which worked".