AI 导读
Anthropic 表示，Claude 设计的蛋白结合体成功结合率为 22% 到 35%，视具体设置而定，而该领域当前的典型成功率在 10% 到 15% 之间。它称部分最强设计的结合紧密度达到已发表最佳 de novo binder 的数倍。配图按靶点列出了 Opus 4.8 与 Mythos Preview 等不同配置的命中率对比。
正文
Designing a binder is an easier process than designing a drug, but it’s a useful proxy. The typical success rate in the field today is between 10% and 15%.
Between 22% and 35% of Claude's designs bound successfully, depending on the setup. Some of its strongest designs bound several times more tightly than the best published de novo binder.
来源：@AnthropicAI · x.com